Overview of genetic array data available

Our studies also collect genetic data, which isn’t listed within CLOSER Discovery yet. A summary of genetic data in CLOSER studies, with links to accessing this data can be seen below.

Researchers wishing to access genetics data from ESRC-funded studies will need to apply to METADAC.

Study name Respondent Number of respondents genotyped Array used Data availability Sample used for DNA extraction Link to data access information
Hertfordshire Cohort Study Study member 1000 Illumina Global Screening Array-24 Coming Q1 2019 Blood N/A
MRC National Survey of Health and Development Study member 2464 Illumina Metabochip Available Blood https://skylark.ucl.ac.uk/NSHD/doku.php?id=mrepo:topics:biologicalsamplesanddna
Study member 2870 Illumina DrugDev Custom chip Available Blood https://skylark.ucl.ac.uk/NSHD/doku.php?id=mrepo:topics:biologicalsamplesanddna
Study member 2793 Illumina NeuroX2 chip Available Blood https://skylark.ucl.ac.uk/NSHD/doku.php?id=mrepo:topics:biologicalsamplesanddna
1958 National Child Development Study Study member 1,504 Affymetrix 500K Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 2,992 Affymetrix v6 Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 6,662 Dynal RELI SSO assay Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 2,922 Illumina 1.2M Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 1,504 Illumina 15K Custom chip Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 1,000 Illumina HiSeq 2500 Available Immortalised LCL https://www.metadac.ac.uk/1958bc **
Study member 872 Illumina Human 610-Quad Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 6,812 Illumina ImmunoBeadShip – Illuminus, GenoSNP Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 5,841 Illumina Metabochip Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 1,436 Infinium 550K v1.1 Available Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 2,604 Infinium HumanHap 550K v3 Available Blood or Immortalised LCL https://ega-archive.org/datasets *
https://www.metadac.ac.uk/1958bc **
Study member 542 MethylationEPIC BeadChip Available Immortalised LCL https://research.ncl.ac.uk/d2k/ourresearch/58forwards/methylation/ **
https://www.metadac.ac.uk/1958bc **
Study member 1,000 Imputed data Available Immortalised LCL https://research.ncl.ac.uk/d2k/ourresearch/58forwards/imputeddata/ **
https://www.metadac.ac.uk/1958bc **
1970 British Cohort Study Study member In field To be determined Coming when funding available Blood N/A
Avon Longitudinal Study of Parents and Children Study member 1,518 Illumina 317 Available Blood or Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Study member 3,233 Illumina 610 Available Blood or Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Study member 1,867 NGS (HiSeq ~6.5x) Available Blood or Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Study member 8,365 Illumina 550 (custom) Available Blood or Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Mother 8,340 Illumina 660 Available Blood or Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Mother and study member pairs 18,000 Illumina 660 + Illumina 550 (custom) Available Blood or Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Mother and father pairs 3,000 Illumina Core Exome Available Blood or Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Mother, father and study member triad 20,000 CNV data Available Blood or Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Study member 869 Illumina Human HT-12 V3 BeadChips (Expression data) Available Immortalised LCL http://www.bristol.ac.uk/alspac/researchers/access/
Mother and study member pairs 1,000 Illumina Infinium 450k methylation array Available Blood http://www.bristol.ac.uk/alspac/researchers/access/
Southampton Women's Survey Study member 1940 Illumina HumanOmniExpress-24 Coming Q1 2020 Cord blood N/A
Mother 1000 Illumina Global Screening Array-24 Coming Q1 2020 Blood N/A
Millennium Cohort Study Mother, father and cohort member triad TBD TBD Coming Q4 2019 Saliva N/A
Understanding Society Study member 10,000 Illumina human core exome array Available Blood https://ega-archive.org/datasets *
https://www.metadac.ac.uk/ukhls/ **

* when genetic data only is requested

** when genetic data is to be linked with other (non-genetic) phenotype/survey data from the study