CLOSER

In 1998, a cohort of men and women born 1931-1939 in the county of Hertfordshire, United Kingdom and still resident there, was recruited to participate in studies examining the interactions between early life, diet, adult lifestyle, and genetic factors as determinants of adult disease. A total of 3225 men and women, aged 59-73 years, were interviewed at home where information was obtained on the participant’s medical and social history by a trained research nurse. Subsequently, 2997 men and women attended a clinic for further investigations.